Termination of non‐coding transcription in yeast relies on both an RNA Pol II CTD interaction domain and a CTD‐mimicking region in Sen1

Z Han, O Jasnovidova, N Haidara, A Tudek… - The EMBO …, 2020 - embopress.org
… In addition, we show that Sen1-dependent termination strictly requires CTD recognition by …
action in the context of a kinetic competition between termination and elongation. We also find …

[HTML][HTML] RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination

JF Victorino, MJ Fox, WR Smith-Kinnaman… - PLoS …, 2020 - journals.plos.org
… proteins are produced by the enzyme RNA Polymerase II. In this work, we … RNA Polymerase
II progression from the start of transcription to the 3’ end of the gene where the nascent RNA

An integrated model for termination of RNA polymerase III transcription

J Xie, U Aiello, Y Clement, N Haidara, M Girbig… - Science …, 2022 - science.org
… Last, we also observed Sen1-dependent release of RNAPIIIs that are paused at sequences
other than T-tracts, for instance, at pausing sites upstream of the canonical terminators, …

[PDF][PDF] Sen1 and Rrm3 ensure permissive topological conditions for replication termination

R Choudhary, J Niska-Blakie, M Adhil, G Liberi… - Cell Reports, 2023 - cell.com
… , but not rrm3, builds up RNA polymerase II (RNPII) at TERs and telomeres. … We then analyzed
the kinetics of appearance and … Sen1dependent RNPII accumulation compared to rrm3D. …

Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis

P Kindgren, M Ivanov, S Marquardt - Nucleic Acids Research, 2020 - academic.oup.com
… -programming of the transcriptional output by RNA polymerase II (RNAPII) that … transcriptional
termination is determined by kinetic competition between the speed of RNAPII transcription

Cotranscriptional RNA processing and modification in plants

S Marquardt, E Petrillo, PA Manavella - The Plant Cell, 2023 - academic.oup.com
between RNA Polymerase II, IV, and V transcription and nascent RNA processing of both
coding and noncoding RNAs. … the competition between splicing and APA, a kinetic competition

Mechanisms of eukaryotic transcription termination at a glance

J Xie, D Libri, O Porrua - Journal of cell science, 2023 - journals.biologists.com
Transcription termination occurs when the RNA polymerase (RNAP) and the nascent transcript
are released from the chromatin. Efficient transcription termination is … an RNA Pol II CTD …

[PDF][PDF] Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII

JB Rodríguez-Molina, S West, LA Passmore - Molecular cell, 2023 - cell.com
… Here, we review eukaryotic transcription termination by RNA polymerase II (RNAPII), …
is a link between transcription termination and chromatin marks of active transcription.Readthrough …

Yeast U6 snRNA made by RNA polymerase II is less stable but functional

KA Lipinski, J Chi, X Chen, AA Hoskins, DA Brow - RNA, 2022 - rnajournal.cshlp.org
… either the two U6 genes compete for transcription factors, … presumably transcribed by different
RNAPs, or that the RNAs compete … Thus, the rapid kinetics of glucose repression and U6-II

Sen1 is a key regulator of transcription-driven conflicts

U Aiello, D Challal, G Wentzinger, A Lengronne… - Molecular Cell, 2022 - cell.com
RNA polymerase II at TRCs within genes and the rDNA and at sites of transcription-transcription
We therefore first analyzed Sen1-dependent alterations on RNAPII distribution focusing …